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Updated: Jul 18, 2026

Electron Cryotomography of Bacterial Cells
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Electron Cryotomography of Bacterial Cells

Published on: May 6, 2010

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低温电子断层扫描揭示了Caenorhabditis elegans微管中的环状内结构

Hao Zhu1, Ming Li1, Meijing Li1

  • 1Tsinghua-Peking Center for Life Sciences, Beijing Frontier Research Center for Biological Structure, McGovern Institute for Brain Research, School of Life Sciences and MOE Key Laboratory for Protein Science, Tsinghua University, Beijing, China.

Biology of the cell
|July 20, 2024
PubMed
概括

研究人员使用先进的成像技术在生物体中的微管内发现了内部环状结构. 这些发现表明,复杂的微管光组件对于细胞功能至关重要.

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The C. elegans Intestine As a Model for Intercellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis at the Single-cell Level: Labeling by Antibody Staining, RNAi Loss-of-function Analy

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In vivo Assessment of Microtubule Dynamics and Orientation in Caenorhabditis elegans Neurons07:43

In vivo Assessment of Microtubule Dynamics and Orientation in Caenorhabditis elegans Neurons

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相关概念视频

Cryo-electron Microscopy01:28

Cryo-electron Microscopy

Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...