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Updated: Jun 20, 2025

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
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使用天然基的新型广谱抗病毒核糖类相应物的设计 - 戒指打开策略

Xingyi Du1,2, Xingxing Yang1,3, Jianyuan Zhao4

  • 1Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, Shenyang, China.

Drug development research
|July 20, 2024
PubMed
概括

研究人员使用"开环"策略开发了新的核类相应物,以对抗RNA病毒感染. 化合物38a显示出广泛的抗病毒活性,在抗A型流感病毒方面表现优于瑞巴维林.

关键词:
这是一种RNA-依赖RNA聚合酶.广泛的抗病毒药物.核酸类型的类似物.

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