死亡率和并发症的风险因素在外围静脉导管相关的黄金葡萄球菌细菌症:一个大型多中心队列研究
A Gallego Rodríguez1, P Duch Llorach1, S Grillo1
1Infectious Diseases Unit, Department of Internal Medicine, Hospital de la Santa Creu i Sant Pau-Institut d'Investigació Biomèdica Sant Pau, Barcelona, Spain; Medicine Department, Universitat Autònoma de Barcelona, Barcelona, Spain.
The Journal of hospital infection
|July 20, 2024
概括
外周静脉导管相关的金黄色葡萄球菌菌病 (PVC-SAB) 导致高死亡率. 及时服用抗生素和全面诊断对于减少这种严重感染的死亡和并发症至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 医院流行病学 医院流行病学
- 临床微生物学 临床微生物学
背景情况:
- 周围静脉导管相关的金黄色葡萄球菌菌病 (PVC-SAB) 是一种严重的医院感染.
- 由于PVC-SAB存在大量死亡和严重并发症的风险.
研究的目的:
- 确定PVC-SAB.患者死亡的独立风险因素.
- 确定与诸如败血症,败血症休克和转移性感染等并发症相关的因素.
主要方法:
- 一项前性队列研究的回顾性分析,涉及PVC-SAB.的成年患者.
- 2011年1月至2019年7月期间,从西班牙的两家三级医院收集的数据.
- 统计分析包括对死亡率和并发症的单变量和多变量评估.
主要成果:
- 该研究在243名患者中发现了256例PVC-SAB病例,30天和90天死亡率分别为18.3%和24.2%.
- 死亡的独立风险因素包括延迟敏感的抗生素给药,败血症,复杂的细菌病,甲素耐药的金黄色细菌 (30天死亡率) 和功能依赖 (90天死亡率).
- 持续的细菌血症和败血症与转移性感染,增加住院时间和内心炎有关.
结论:
- 尽管如此,PVC-SAB仍与高死亡率有关.
- 及时服用适当的抗生素对于改善患者的治疗结果至关重要.
- 要检测转移性并发症,需要进行彻底的诊断评估,特别是在患有持续性细菌病或心脏器械的患者中.
相关概念视频
01:26Factors Affecting the Risk of Infection
11.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.5K
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.1K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.1K
01:22Healthcare Associated Infections II: Preventive Measures
2.6K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.6K
01:30Pneumonia III: Complications and Assessment
197
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
197