TAZ降低了ANXA1表达的调节,以调节骨髓髓细胞与骨髓中介质细胞的相互作用

Samuel O Abegunde1, Stacy Grieve2, Tony Reiman3

  • 1Department of Biology, University of New Brunswick, Saint John, NB, Canada; Dalhousie Medicine NB, Saint John, NB, Canada; Vancouver General Hospital, Vancouver, BC, Canada.

PubMed
概括

TAZ蛋白通过降低ANXA1表达的调节,抑制多发性髓瘤 (MM) 细胞迁移和与骨髓 stromal 细胞的相互作用. 这确定了ANXA1作为减少MM中促进瘤相互作用的潜在目标.

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