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基于纤维素和碳醇971的胃性控制释放配方设计,优化和基于生理学上的药物动力学建模Ondansetron化minitablets

Tahmina Maqbool1, Rabia Ismail Yousuf1, Farrukh Rafiq Ahmed1

  • 1Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi 75270, Pakistan.

International journal of biological macromolecules
|July 20, 2024
PubMed
概括

这项研究开发了优化Ondansetron (OND) 胃阻塞浮式迷你盘,用于长期控制术后恶心和吐 (PONV). 新配方显示了可比的生物可用性和改善的药物释放概况,以便更好地满足患者的要求.

关键词:
纤维素以太是一种纤维素.有控制释放的释放.胃阻塞药物输送系统 (GRDDS) 是一种药物输送系统.PBPK (基于生理学的药理动力学模型)QbD (通过设计的质量)

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