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Updated: Jun 20, 2025

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由于持续高脂的UCP1降低,促进NK细胞亡,加剧非酒精性肝纤维化.

Min Gu1,2, Yu Zhang1,3, Zhijie Lin1,2

  • 1Department of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou, PR China.

Cell death & disease
|July 20, 2024
PubMed
概括

自然杀手 (NK) 细胞中脱离蛋白1 (UCP1) 缺乏会损害它们的功能,恶化非酒精性脂肪肝炎 (NASH) 和肝纤维化. 高脂质进一步降低UCP1,促进NK细胞死亡和疾病进展.

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