环境CO和温度或相对湿度之间的相互作用对中风住院治疗风险的影响
Zhuo Liu1,2, Hua Meng1,2, Xingtian Wang3
1School of Public Health and Management, Ningxia Medical University, Yinchuan, 750001, China.
Scientific reports
|July 20, 2024
概括
一氧化碳 (CO) 暴露会增加中风风险. 碳化合物与高温有协同作用,与高湿度有敌对作用,根据年龄和性别不同影响中风风险.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 心血管疾病 心血管疾病
背景情况:
- 已知环境一氧化碳 (CO),温度和湿度对中风的独立影响.
- 这些环境因素和易受影响的人群之间的相互作用仍然不清楚.
研究的目的:
- 调查环境CO,温度和湿度对中风住院治疗的相互作用影响.
- 为了识别这些环境暴露的敏感人群.
主要方法:
- 利用来自中国宁夏 (2014-2019) 的中风住院数据和环境数据.
- 采用了延迟效应的一般化添加模型和相互作用分析的双变量响应表面模型.
- 对相对过度风险 (RERI) 的分层分析确定了敏感群体.
主要成果:
- 高温和CO显示出对出血和缺血性中风的协同作用.
- 低相对湿度和CO对出血性中风和老年人缺血性中风具有协同作用.
- 较高的相对湿度和CO对男性和女性的缺血性中风住院治疗产生了对抗作用.
结论:
- 暴露于二氧化碳会增加出血和缺血性中风住院的风险.
- 二氧化碳,温度和湿度之间的相互作用影响中风风险,观察到显著的年龄和性别差异.
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