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Updated: Jun 20, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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在T-ALL/LBL中,PIM1是JAK/STAT路径突变调解的白血病原体效应的潜在治疗标

Antonio Lahera1,2,3, Laura Vela-Martín4,5,6, Pablo Fernández-Navarro7,8

  • 1Department of Biology, Universidad Autónoma de Madrid, Madrid, 28049, Spain. a.lahera@cbm.csic.es.

NPJ precision oncology
|July 20, 2024
PubMed
概括

前体T细胞急性淋巴细胞白血病/淋巴瘤 (T-ALL/LBL) 涉及JAK/STAT通路突变. 使用PIM447准PIM1过度表达,有望减少白血病发生和异常通路激活.

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