使用心血管磁共振评估埃布斯坦异常患者的左心室病理:超越右心脏
Aditi Gupta1, Luciana Da Silva2,3,4, Li Wang4
1Division of Pediatric Cardiology, Heart Institute, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA. guptaa14@upmc.edu.
埃布斯坦异常 (EA) 通常涉及左心室 (LV) 功能障碍,可通过心脏MRI (CMR) 检测. 在EA患者中,手术前的LV功能障碍与更长的住院时间和术后支持需求增加有关.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 遗传性心脏病是一种先天性心脏病.
背景情况:
- 埃布斯坦异常 (EA) 是一种右心脏形.
- 左心室 (LV) 异常可以影响EA患者的外科手术结果.
- 在EA患者的LV可能会表现出超曲结和功能/应变受损.
研究的目的:
- 用心脏MRI (CMR) 来评估埃布斯坦异常 (EA) 患者的手术前左心室 (LV) 结构和功能.
- 将EA患者的LV特征与健康对照进行比较.
- 评估 LV 功能障碍与术后结果之间的关系.
主要方法:
- 对47名EA患者和年龄匹配的对照进行了回顾性单中心研究.
- 术前心脏MRI (CMR) 用于LV和RV体积,功能和应变分析.
- 测量LV非压缩:压缩 (NC/C) 比率和三门位移指数.
主要成果:
- 36%的EA患者在CMR上表现出轻微的手术前LV功能障碍,经常无法通过心声图检测到.
- 减少的LV喷射分数与较低的全球周长和纵向应变相关.
- 手术前的 LV 功能障碍与更长的上腺素使用和手术后住院时间有关.
结论:
- 手术前的LV功能障碍在EA患者中很常见,CMR可以很好地检测到.
- 在EA中LV功能障碍会影响经营前管理.
- 需要对更大的队列和更长的随访进行进一步的研究.
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