相关实验视频
Updated: Jun 20, 2025

10:36
Probiotic Studies in Neonatal Mice Using Gavage
Published on: January 27, 2019
19.4K
患有食物蛋白肠球炎的婴儿的肠道微生物群
Jing Xiong1,2,3,4,5, Yu-Jue Ma1,2,3,4,5, Xing-Sheng Liao6
1Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Pediatric research
|July 20, 2024
概括
婴儿的食物蛋白诱导肠道炎综合征 (FPIES) 与肠道失调有关. 不同的配方,如广泛化配方 (EHF) 和基于氨基酸的配方 (AAF),对肠道微生物群和短链脂肪酸 (SCFA) 产生不同的影响.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 微生物组研究 微生物组研究
- 临床营养学 临床营养学
背景情况:
- 患有食物蛋白诱导肠道炎综合征 (FPIES) 的婴儿经常出现肠道失调.
- 广泛化配方 (EHF) 和基于氨基酸的配方 (AAF) 对FPIES肠道微生物群和短链脂肪酸 (SCFA) 的影响需要进一步调查.
研究的目的:
- 调查EHF和AAF对被诊断患有FPIES的婴儿肠道微生物群和SCFA的影响.
- 为了比较肠道微生物组成和SCFA概况的婴儿食EHF和AAF之间的婴儿.
主要方法:
- 在诊断时和诊断后四周内,从30名患有FPIES的婴儿收集了便样本.
- 用16S rRNA基因测序分析了肠道微生物群.
- 通过气色谱-质谱法量化SCFA.
主要成果:
- 与对照组相比,FPIES婴儿表现出改变的微生物多样性,减少Bifidobacterium和增加的六酸.
- 食EHF的婴儿随着时间的推移显示微生物丰富度下降,黄油和六酸减少.
- 接受AAF养的婴儿保持了微生物多样性和丰富性,埃舍里基亚-西格拉菌的丰富性增加.
结论:
- 患有FPIES的婴儿存在肠道失生症.
- 在FPIES婴儿中,EHF和AAF差异调节肠道微生物群和SCFA概况.
- 了解这些配方特异性影响可以为FPIES管理提供养实践选择的信息.
相关概念视频
Anatomy of the Intestines
71.7K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
71.7K
Bacterial Flora of the Large Intestine
414
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
414
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
331
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
331

