对唐氏综合征儿童阻塞性睡眠呼吸暂停的桃体切除术的长度成功
Obinna R Diala1, Pinar Polat2,3, Kaci Pickett-Nairne4,5
1Department of Family Medicine and Population Health, Virginia Commonwealth University, Richmond, Virginia, USA.
概括
患有唐氏综合征 (DS) 和轻度阻塞性睡眠呼吸暂停 (OSA) 的儿童在桃体切除和腺切除 (T&A) 后可能会出现症状恶化. 定期的随访多睡眠图 (PSG) 对于监测疾病进展至关重要.
科学领域:
- 儿科耳鼻喉科 儿科耳鼻喉科
- 睡眠医学 睡眠医学
- 遗传学 是一个遗传学.
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 在患有唐氏综合征 (DS) 的儿童中非常普遍.
- 桃切除术和腺切除术 (T&A) 是儿童OSA的常见治疗方法,但DS患者的长期结果尚未得到充分证实.
研究的目的:
- 评估T&A在DS儿童的长期多梦和症状结局.
- 为了确定T&A在治疗DS儿童的OSA中的有效性是否随着时间的推移而减弱.
主要方法:
- 在2009年至2015年期间接受过T&A的DS儿童的回顾性图表审查.
- 纳入标准:初始术后多睡眠图 (PSG) 具有阻塞性呼吸暂停/呼吸暂停指数 (OAHI) <5.
- 通过随后的诊所访问和PSG,OAHI监测,打和复发时间来评估结果.
主要成果:
- 在57名T&A后轻度OSA儿童中,33%的OAHI在第二次PSG时≥5.
- 在接受第三次PSG的患者中,有22%的患者进展为中度/重度OSA.
- 30%的初始队列进展为中度/严重的OSA,随访时间中位数为2.3年.
结论:
- 患有DS和T&A后轻度OSA的儿童有风险在两年内发展为中度或重度OSA.
- 建议在手术后大约两年进行PSG,以确定需要进一步干预的儿童.
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