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Updated: May 3, 2026

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在人类疾病中,液态-液态相分离的生物信息学方法

Jun Sun1,2, Yilong Chen1,2, Ruiye Bi3

  • 1Department of Thoracic Surgery and West China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.

Chinese medical journal
|July 21, 2024
PubMed
概括

液-液相分离 (LLPS) 形成细胞结构,对生物过程至关重要,但与疾病有关. 本综述涵盖了LLPS研究,其疾病相关性,以及生物信息学在理解这些关键生物分子凝聚物的作用.

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Overview Of Cell Separation And Isolation01:20

Overview Of Cell Separation And Isolation

Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.
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