管道与非管道流量转移器治疗M1动脉瘤:系统性审查和元分析
Yigit Can Senol1, Atakan Orscelik2, Cem Bilgin2
1Department of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.
The neuroradiology journal
|July 21, 2024
概括
流量转移装置有效治疗具有高闭塞率的M1动脉瘤. 管道栓塞装置 (PEDs) 与其他流量转移器 (FDs) 相比,具有类似的安全配置文件,显示出更高的完全封闭性.
科学领域:
- 神经外科 神经外科
- 干预性神经辐射学
- 血管外科 血管外科
背景情况:
- 流量转移器 (FD) 对威利斯圆的静脉动脉瘤的治疗越来越常见.
- 在内血管治疗中,M1段动脉瘤存在独特的挑战.
- 系统性审查和元分析以评估M1动脉瘤中FD的疗效和安全性.
研究的目的:
- 系统地审查和对M1动脉瘤FD栓塞的临床和放射性结果进行元分析.
- 为了比较管道栓塞装置 (PED) 和其他FD设备之间的结果.
- 评估闭塞率,并发症和功能结果.
主要方法:
- 在主要数据库 (PubMed,科学网,Embase,Scopus) 进行全面的文献搜索,截至2024年5月.
- 包含了13项研究,包括112名患者 (58名PED,54名非PED) 进行元分析.
- 使用R软件分析血管学阻塞,缺血/出血并发症,修改的兰金尺度 (mRS) 和静脉支架狭窄症.
主要成果:
- 在用FDs治疗的M1动脉瘤中,整体充足的闭塞率为85.1%.
- 管道栓塞装置 (PED) 的完全封闭率显著高 (72.9%) 与非PED FD (41.6%) 相比.
- 缺血并发症的比较率 (9.9%的PED与9.0%的非PED) 和良好的功能结果 (97.1%的mRS 0-2 PED与100%的非PED).
结论:
- 对M1动脉瘤的流量转移器治疗产生了高阻塞率和有利的安全概况.
- 与其他用于M1动脉瘤的FD装置相比,PED与更高的完整动脉瘤闭塞率有关.
- 进一步的研究可能会探索这种动脉瘤子集的长期结果和特定设备性能.
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