智力障碍/边缘认知功能的个体中精神性非发作:通过对比研究进行表征
Emilia Ricci1, Katherine Turner1, Emanuele De Ponti1
1Child Neuropsychiatry Unit, Epilepsy Center, San Paolo Hospital, Department of Health Sciences, University of Milan, Milan, Italy.
Seizure
|July 21, 2024
概括
患有精神性非发作 (PNES) 和轻度智力障碍或边缘智力功能 (ID/BIF) 的人与具有正常认知的人相比,表现出类似的临床特征和治疗结果. 认知行为疗法 (CBT) 对这两个群体都有效.
科学领域:
- 神经学 神经学
- 神经心理学 神经心理学
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 精神性非发作 (PNES) 是一种功能神经系统疾病.
- 了解智力障碍 (ID) 或边缘智力功能 (BIF) 患者的PNES对于量身定制的临床管理至关重要.
- 以前的研究还没有完全阐明这种特定人群的临床特征和治疗反应.
研究的目的:
- 与正常认知功能的人相比,在ID/BIF患者中描述PNES.
- 确定可能为PNES改善的临床管理协议提供信息的差异.
- 评估当前治疗策略在认知功能组的有效性.
主要方法:
- 通过视频脑电图 (vEEG) 诊断的PNES患者 (≥14岁) 的回顾性,观察性,单中心研究.
- 包括接受全面神经心理评估的患者.
- 两个组的比较:正常认知 (IQ≥85) 和轻度的ID/BIF (每个n=25),分析了人口统计,临床和vEEG数据.
主要成果:
- 在ID/BIF和正常认知组之间没有发现统计学上显著的临床差异.
- 诊断延迟和处方不合适的抗发作药物 (ASM) 在两组之间是可比的.
- 包括认知行为疗法 (CBT) 在内的行为心理治疗方法,在两个小组中都显示出类似的积极结果.
结论:
- 在轻度ID/BIF患者中,PNES的临床管理与正常认知功能患者相似.
- 人口统计学,临床和形学数据在各认知层面上都是可比的.
- 认知行为疗法 (CBT) 是对PNES的有效治疗方法,无论轻度的ID/BIF状态如何;对于中度/严重的ID,需要进一步研究.
相关概念视频
01:13Seizures: Classification
328
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
328
01:24Arteries of the Lower Limbs
182
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
182
01:29Intellectual Disability
48
Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
48