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Updated: Jun 20, 2025

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PARP4 与 hnRNPM 相互作用,以调节肺癌进展期间的拼接

Yi Fei Lee1,2, Cheryl Zi Jin Phua1, Ju Yuan1

  • 1Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 60 Biopolis Street, Genome, Singapore, 138672, Singapore.

Genome medicine
|July 21, 2024
PubMed
概括

聚 ((ADP-ribose) 聚合酶4 (PARP4) 通过调节结合,独立于体复合体,在肺腺癌中起到瘤抑制作用. 它与hNRNPM的新奇相互作用突出显示了癌症进展中的拼接失调.

关键词:
功能性基因组学是一种功能性基因组学.疾病的机制疾病的机制.非小细胞肺癌的非小细胞肺癌.

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