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Updated: Jun 20, 2025

Stimulation of Notch Signaling in Mouse Osteoclast Precursors
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Published on: February 28, 2017

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哈卡伊是一种新的Runx2相互作用蛋白,通过拯救Runx2从Smurf2介导的蛋白酶体降解中来增加骨质细胞分化

Vishal Upadhyay1,2, Shivani Sharma2,3, Arppita Sethi1,2

  • 1Division of Cancer Biology, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.

Journal of cellular physiology
|July 22, 2024
PubMed
概括

哈卡伊是一种E3泛素酶,通过稳定Runx2促进骨形成,Runx2是骨质母细胞分化的关键调节者. 哈卡伊保护Runx2免受降解,为骨质疏松症提供潜在的治疗点.

关键词:
哈卡伊 (Hakai) 是一个古老的城市.马尔迪TOF/TOF/马尔迪土耳其土耳其土耳其在Runx2中使用Runx2.斯默夫2 在线观看骨质母细胞 (osteoblasts) 是一个骨质细胞.骨质疏松症是一种骨质疏松症.

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A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation09:37

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