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Updated: Jul 28, 2026

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有效的Dlx2介导的天体细胞转化为神经元,并通过NeuroD1抑制神经炎症

Min-Hui Liu1,2, Yu-Ge Xu1, Xiao-Ni Bai1

  • 1Guangdong-HongKong-Macau Institute of CNS Regeneration (GHMICR), Jinan University, Guangzhou, China.

Developmental neurobiology
|July 22, 2024
PubMed
概括

神经转录因子Dlx2将星体细胞转化为大脑中的神经元. 这种天体细胞转化为神经元 (AtN) 显示出神经修复的潜力,但需要管理神经炎症,特别是在白质中.

关键词:
Dlx2 在线阅读这是一个神经D1D1的过程.细胞转化细胞的转化在体内进行生物重编程.神经炎症是一种神经炎症.条纹体的条纹体.

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相关概念视频

Forced Transdifferentiation01:28

Forced Transdifferentiation

Transdifferentiation, also known as lineage reprogramming, was first discovered by Selman and Kafatos in 1974 in silkmoths. They observed that the moths’ cuticle-producing cells transformed into salt-producing cells. Many such cases of natural transdifferentiation occur in organisms. In humans, pancreatic alpha cells can become beta cells. In newts, the loss of the eye’s lens causes the pigmented epithelial cells to transdifferentiate into the lens cells.
Artificial transdifferentiation occurs...