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Updated: Jun 20, 2025

Isolation and Cultivation of Neural Progenitors Followed by Chromatin-Immunoprecipitation of Histone 3 Lysine 79 Dimethylation Mark
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ASH1L中的PHD-BAH域可以识别H3K4甲基化并调节胆瘤癌的恶性行为

Xiang-Yu Zhang1, Yue Li2

  • 1Clinical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.

Anti-cancer agents in medicinal chemistry
|July 22, 2024
PubMed
概括

ASH1L的PHD-BAH域与H3K4me2结合,这对胆管癌细胞存活至关重要. 突变会破坏这种相互作用,通过PSMB基因调节影响细胞增殖和细胞亡.

关键词:
在 ASH1L 中.这就是CHOL癌症的原因.这是一种H3K4me2.在 PHD-BAH 域名中.PSMB家族的基因是PSMB家族的基因.这是W2603A突变.

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