患有尿路炎的韩国男性喉淋病的患病率和分子特征
Kyoung Ho Roh1, Changseung Liu2, Young Hee Seo3
1Department of Laboratory Medicine, National Health Insurance Ilsan Hospital, Goyang, Korea.
Annals of laboratory medicine
|July 22, 2024
概括
喉淋病在韩国男性尿路炎中很常见,影响30.5%的病例. 这凸显了对高风险个体进行喉查的必要性,以管理这种感染储备.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 喉淋病带来了诊断和治疗方面的挑战.
- 喉可以作为一个Neisseria gonorrhoeae的水库.
- 了解喉淋病的患病率对于有效控制至关重要.
研究的目的:
- 为了确定被诊断患有尿路炎的韩国男性中喉淋病的患病率.
- 为了分析Neisseria gonorrhoeae从喉和尿道感染中分离的分子特征.
- 评估这些分离物的抗微生物敏感性模式.
主要方法:
- 招募了72名患有尿路炎症状的男性患者.
- 尿道和喉样本被采集用于菌培养和多重实时PCR (mRT-PCR).
- 进行了Neisseria gonorrhoeae多抗原序列类型 (NG-MAST) 和抗菌敏感性测试.
主要成果:
- 多重实时PCR检测到72名患者中有59名 (81.9%) 的冠状病毒.
- 喉淋病在18名患者中存在 (30.5%的阳性淋病菌患者).
- 抗微生物敏感性测试显示抗 ceftriaxone (2.9%) 和cefixime (14.7%) 的耐药性,但对阿齐思罗米和spectinomycin.
结论:
- 在韩国男性患有淋巴结核性尿路炎时,淋巴结核的患病率显著 (30.5%).
- 对于高风险人群,建议对喉淋病进行查.
- 尽管出现了耐药性,但 ceftriaxone 仍然是对喉淋病的推治疗方法.
相关概念视频
01:26Sexually Transmitted Infections
293
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
293
01:30Acute Pharyngitis
555
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
555
01:23Chronic Pharyngitis
1.6K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
1.6K
00:46Genomic DNA in Prokaryotes
43.7K
The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
Genomic Diversity in Bacteria
Although bacterial genomes are much...
43.7K