全球坎塔里丁研究的图书统计分析和系统审查
Tianmu He1,2, Cancan Duan3, Wenzhong Feng3
1School of Basic Medicine, Zunyi medical University, Zunyi 550025, China.
Current pharmaceutical biotechnology
|July 22, 2024
概括
坎塔里丁 (CTD) 是一种传统的癌症治疗方法,正在研究其药理学. 研究强调蛋白酸酶2A (PP2A) 是一个关键领域,未来的研究重点是PP2A调节和CTD.
科学领域:
- 药理学 药理学是指药理学的学科.
- 生物化学 生物化学
- 在瘤学瘤学.
背景情况:
- 康塔里丁 (CTD) 是一种来自泡甲虫的天然化合物,在癌症治疗方面有着悠久的历史.
- CTD及其类似物被用作辅助疗法,并与化疗和放射治疗一起使用.
- 确切的CTD的药理机制仍然不完全理解.
研究的目的:
- 进行对康达里丁 (CTD) 研究的文献分析.
- 确定CTD药理学的关键研究趋势,有影响力的机构和新兴领域.
- 综合有关CTD作用机制和潜在毒性的当前知识.
主要方法:
- 从科学网络核心集合 (1991-2023) 收集了1611篇关于CTD的出版物.
- 使用CiteSpace,VOSviewer和Scimago Graphica进行文献计量分析.
- 进行了系统审查,以确定研究热点和未来方向.
主要成果:
- CTD研究主要集中在中国和美国,纽卡斯尔大学是主要机构.
- 关键的研究领域包括蛋白酸酶2A (PP2A),人类胆囊癌,Aidi注射和细胞亡.
- 确定了该领域的杰出研究人员和期刊.
结论:
- 图书统计分析显示,蛋白质酸酶2A (PP2A) 和CTD类似物构成了CTD研究的知识基础.
- 未来的研究应该集中在PP2A子单元调节和CTD的毒理机制 (肝毒性,毒性,心毒性) 上.
- 了解PP2A的作用和CTD的毒性被认为是CTD研究的关键前沿.
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