在COVID-19期间,成年结核病患者的严重结局
T Jacobs1, E Morden1,2, M Smith1,3
1Health Intelligence Directorate, Western Cape Health and Wellness, Provincial Government of the Western Cape, Cape Town, South Africa.
IJTLD open
|July 22, 2024
概括
由于COVID-19的流行,结核病 (TB) 的诊断减少了22%. 然而,在此期间,入院结核病患者的死亡风险显著增加,这凸显了综合健康策略的必要性.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染病控制和控制传染病
背景情况:
- 在全球范围内,COVID-19大流行需要严格的公共卫生措施 (PHSM).
- 这些措施可能会破坏南非西开普省的结核病 (TB) 计划.
研究的目的:
- 评估PHSM对西开普省结核病例率和死亡率的影响.
- 评估不同PHSM严格级别的结核病例检测和患者结果的变化.
主要方法:
- 追溯队列研究的设计.
- 在疫情前和PHSM期间 (2020年3月至2021年9月) 分析了新的结核病例率和住院死亡率.
- 利用中断时间序列和后勤回归,根据患者的关键特征进行调整.
主要成果:
- 在PHSM期间,每月结核病例的平均减少率为22%.
- 结核病入院期间死亡风险增加,调整后的几率比率在不同PHSM水平之间从1.36到1.44不等,与大流行前的时代相比.
结论:
- 在2020年3月至2021年9月期间,确诊结核病例的减少和严重结核病结果的增加发生了.
- 优先考虑结核病计划的恢复和将结核病管理纳入未来的流行病应对措施至关重要.
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