合成和描述含有imine功能组的基甲基酸寡合体,用于立体石刻
Nuttapol Risangud1,2, Jittima Mama3, Piyarat Sungkhaphan1
1National Metal and Materials Technology Center, National Science and Technology Development Agency, 111 Thailand Science Park, Phahonyothin Road, Klong Luang, Pathum Thani 12120, Thailand.
ACS omega
|July 22, 2024
概括
一种基于 furan 的新型甲基酸寡合物 (FBMO) 由可持续资源合成,用于立体石刻. 这种新材料允许可调整的3D打印特性,并表现出非细胞毒性行为,为先进的应用开辟了道路.
科学领域:
- 聚合物化学 聚合物化学
- 材料科学 材料科学 材料科学
- 生物材料工程 生物材料工程
背景情况:
- 5-基甲基 (5-HMF) 是一种可持续的平台化学物质,来自生物质.
- 基于的聚合物具有独特的特性,但需要功能化来实现3D打印等先进应用.
- 立体石刻 (Stereolithography,SLA) 是一种3D打印技术,使用可光固化树脂.
研究的目的:
- 为了合成基于的甲基酸寡合物 (FBMO) 与SLA应用的imine功能组.
- 调查FBMO度对树脂特性和3D打印物体特征的影响.
- 评估开发的3D打印材料的机械,热和细胞毒性质.
主要方法:
- 通过5-HMF和氨基乙醇的阴化合成FBMO.
- 通过将FBMO与PEGDMA和TEGDMA等稀释剂结合起来,制备光敏树脂.
- 使用FTIR,1HNMR和大小排除色谱对FBMO和树脂进行表征.
- 评估3D打印样本的树脂质学,打印保真度,机械性能,热稳定性和细胞毒性.
主要成果:
- FBMO已成功合成和表征.
- 树脂粘度可以通过调整FBMO比率从0.04到0.28Pa s进行调整.
- 3D打印的标本显示出高保真度的CAD模型和压缩模块从0.53到144MPa.
- 印刷材料显示对猪体细胞没有细胞毒性.
结论:
- 开发了一种基于 furan 的新型甲基酸寡合物 (FBMO) 用于立体石刻.
- 该配方允许控制树脂粘度和3D打印部件可调节的机械性能.
- 印刷材料的非细胞毒性表明生物医学应用的潜力.
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