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在目标导向的大型输血中,使用血小板图量身定制输血策略:对输血需求和临床结果的影响

P A Prethika^1,2, Ganesh Mohan², Shamee Shastry²

¹Department of Immunohematology and Blood Transfusion, Apollo Hospitals, Chennai, Tamil Nadu, India.

Asian journal of transfusion science

|July 22, 2024

概括

基于血小板表 (TEG) 的指导目标的大型输血 (MT) 减少了出血性休克患者的血液成分使用和凝血病. 这种方法改善了患者的生存率,而不是基于配方的协议.

科学领域:

创伤和紧急医疗医学
输血医学输血医学
关键的护理关键的护理

背景情况:

出血性休克复苏通常使用基于配方的大规模输血 (MT) 协议.
基于血小板显微镜 (TEG) 的基于目标的MT的有效性需要进一步的临床结果比较.

研究的目的:

为了比较基于配方 (1:1:1) 和TEG引导的基于目标的MT协议在患有出血性休克的患者之间的临床结果.

主要方法:

一项追溯前性病例控制研究比较了两个MT协议超过2年.
患者根据受伤严重程度进行了匹配. 分析了血液成分的利用率,临床结果,并发症和死亡率.

主要成果:

以TEG为指导的MT将血液成分利用率降低了17.7% (1560对1867单位).
在TEG组中,较少的患者患有凝血病 (6.9%与31.8%相比),更多的患者无需输血支持 (75%与65.4%相比).
在TEG引导组中观察到死亡率降低了10%.

结论:

以TEG为指导的基于目标的MT优化了血液成分的使用,并减少了凝血病.
这种方法提高了在出血性休克复苏中患者的生存率.

关键词:

血液的利用血液的利用目标定向的大规模输血.发生出血性休克.大规模的输血输血.血小板结晶图 (Thromboelastogram) 是一种血小板结晶图 (Thromboelastogram) 的形式.

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