血清水平的估计在血小板捐赠者中
P Arpitha1, Ravindra Prasad Thokala1
1Department of Transfusion Medicine, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.
Asian journal of transfusion science
|July 22, 2024
概括
使用酸酸糖的血小板转移是安全的,在术后暂时有和pH值下降. 亚菲雷斯捐赠者的水平和pH值在30分钟内恢复.
科学领域:
- 输血医学 输血医学
- 血液学 血液学 血液学
背景情况:
- 阿菲雷西斯是一种常见的收集单一捐赠血小板 (SDP) 的方法.
- 酸酸乳 (ACD) 用作抗凝剂,化和可能改变平衡.
- 这可能导致低血症和捐赠者的急性不良事件.
研究的目的:
- 为了研究为血小板捐献而经历表的个体的平衡.
- 为了评估对捐赠者的水平和pH的阿菲雷斯程序的影响.
主要方法:
- 一项涉及50名自愿SDP捐赠者的横截面研究.
- 测量包括总和电离,pH值和血清白蛋白在基线.
- 在手术后立即和手术结束后30分钟测量了电离和pH值.
主要成果:
- 离子水平立即下降,但在30分钟内恢复到基线.
- 在手术后立即观察到pH值显著下降.
- 酸盐的代谢似乎在30分钟内基本完成.
结论:
- 通过异位抽取单个供体血小板的采集通常是安全的,具有轻微的不良影响.
- 在捐赠者中,酸盐的潜在毒性并不显著.
- 在血小板转化完成后的30分钟内,平衡恢复.
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