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Updated: Jun 20, 2025

Author Spotlight: Characterizing DNA G-Quadruplex by Bis-3-Chloropiperidine Based Chemical Mapping
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通过bis-intercalators准DNA结点,诱导具有强大的抗瘤作用的拓变化

Shih-Chun Huang1,2, Chia-Wei Chen3, Roshan Satange2

  • 1Doctoral Program in Medical Biotechnology, National Chung Hsing University, Taichung 402, Taiwan.

Nucleic acids research
|July 22, 2024
PubMed
概括

针对DNA结点的双间隔器在癌症治疗方面表现有前途. 这些化合物改变了DNA结构,抑制了对癌细胞生存和增殖至关重要的酶.

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