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Updated: Jun 20, 2025

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探索跨子单元界面突变对病毒样粒子结构和稳定性的影响

Paige E Pistono1, Junyi Xu1, Paul Huang1

  • 1Department of Chemistry, University of California, Berkeley, California 94720, United States.

Biochemistry
|July 22, 2024
PubMed
概括

具有突变的工程菌MS2病毒样颗粒 (VLPs) 显示了改变的组装状态和增强的稳定性. 这些修改后的VLP保持了药物输送能力,为治疗应用提供了对蛋白质自组装和VLP工程的见解.

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