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检查视网膜静脉封闭性抗VEGF内治疗后的胆道结构变化

Erdem Dursun¹, Baki Derhem², Seval Çobanoğlu³

¹Faculty of Medicine, Ophthalmology Department, Kırıkkale University, Seyrantepe Mh. Asude Kent Sitesi C Blok no:22 Yahsihan, Kırıkkale, Turkey. erdem.drsn@gmail.com.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

|July 22, 2024

概括

在视网膜静脉封闭 (RVO) 患者中,静脉内血管增长因子 (VEGF) 治疗改善了视力敏度和改变了后部细分结构. 冠状血管度指数增加,而斑点和冠状血管厚度在治疗后下降.

科学领域:

眼科医生眼科眼科
视网膜疾病视网膜疾病
血管生物学血管生物学

背景情况:

视网膜静脉封闭 (RVO) 影响眼睛后部结构.
内抗血管内皮生长因子 (VEGF) 治疗是一种常见的RVO治疗方法.

研究的目的:

为了研究抗VEGF治疗对RVO患者后部部分的影响.
评估斑点的变化,胸膜厚度和胸膜血管度指数 (CVI).

主要方法:

在6个月内对29个RVO眼睛进行前性纵向研究.
通过光谱域光学连贯性断层扫描评估最佳校正的视力敏度 (BCVA),黄斑和胸膜厚度,以及CVI.
将治疗眼睛与同类眼睛和年龄/性别匹配的对照进行比较.

主要成果:

在注射后的第六个月,BCVA显著改善.
治疗后减少了中央黄斑厚度,底状厚度和状区域.
增加CVI,特别是在第一个月内,表明血管变化.

结论:

冠状结构的变化与RVO活性相关.
监测胆道变化可以预测RVO中抗VEGF治疗的疗效.

关键词:

中部黄斑厚度中部黄斑厚度冠状腺的厚度冠状腺的厚度冠状腺血管度指数冠状腺血管度指数视网膜静脉封闭视网膜静脉封闭血管内皮生长因子血管内皮生长因子

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