身体活动和疲劳症状:神经典型成年人和患有慢性多症状疾病的人
Alex Boruch1,2, Grace Branchaw1,2, Patrick J O'Connor3
1Research Service, William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.
Current topics in behavioral neurosciences
|July 22, 2024
概括
身体活动在健康的成年人中增加了能量,但在患有慢性多症状疾病 (CMI) 的人中加剧了疲劳. 需要更多的研究来了解运动的影响和长期COVID和ME/CFS等疾病的潜在益处.
科学领域:
- 运动生理学 运动生理学
- 神经科学是一个神经科学.
- 慢性疾病研究 慢性疾病研究
背景情况:
- 低至中等强度的体力活动通常会提高神经类型个体的能量水平.
- 相反,患有慢性多症状疾病 (CMI) 的个人,包括长期COVID,海湾战争疾病 (GWI) 和肌痛性脑筋炎/慢性疲劳综合征 (ME/CFS),在类似的运动后经常经历疲劳增加.
- 由于有限的数据,定期的中等强度体力活动对CMI中疲劳和能量的长期影响尚未得到充分证实.
研究的目的:
- 审查当前对运动对神经类型成年人和CMI患者疲劳和能量的急性和慢性影响的理解.
- 探索这些人群中运动引起的疲劳或能量增强的潜在机制.
- 强调需要进一步研究运动作为潜在的CMI疾病修饰治疗的必要性.
主要方法:
- 文献综述和综合现有关于身体活动,疲劳和能量水平的研究.
- 在神经类型人群和被诊断患有CMI的个体之间比较运动反应.
- 对与炼和疲劳相关的拟议的神经生物学和病理生理机制的分析.
主要成果:
- 神经类型的成年人通常在急性炼后报告过渡性能量改善,在定期中等强度活动时,疲劳和活力的适度改善.
- 患有CMI的个体在急性炼后经常经历疲劳恶化的情况,在短期的定期活动中报告的改善有限或没有显著改善.
- 在CMI中,运动对慢性影响的数据不足以得出最终的结论.
结论:
- 运动在神经类型个体和CMI患者之间引起了不同能量和疲劳水平的反应.
- 驱动这些对比效应的机制尚不清楚,但可能涉及神经,免疫和自主系统内的复杂相互作用.
- 进一步的研究至关重要,以确定慢性体力活动是否可以作为一种有益的,对CMI患者的疾病修饰干预措施.
相关概念视频
01:24Muscle Recovery and Fatigue
2.0K
Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...
2.0K
01:21Fatigue
180
Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
180
01:23Assessment of the Cardiovascular System I: Subjective Data
299
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
299
01:18Factors Affecting Illness
4.2K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
For instance, risk factors are connected to illness,...
4.2K