氧化平衡得分与成年人结石之间的关联
Qiongqiu Chen1, Wenshuo Bao1, Xianghui Kong1
1Department of Urology, Wenzhou People's Hospital, Wenzhou, 325000, P.R. China.
World journal of urology
|July 22, 2024
概括
较高的氧化平衡得分 (OBS) 与成人结石患病率较低有关. 保持良好的OBS可能有助于减少患结石的风险.
科学领域:
- 营养与饮食学 营养与饮食学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 公共卫生 公共卫生
背景情况:
- 结石是一种常见的健康问题,具有多因素的原因.
- 氧化压力在各种慢性疾病中起作用,包括潜在的结石形成.
- 氧化平衡评分 (OBS) 量化了影响氧化平衡的饮食和生活方式因素.
研究的目的:
- 调查氧化平衡得分 (OBS) 与一般成人人口中结石患病率之间的关联.
- 为了确定较高的OBS是否与较低的结石患病概率相关.
- 探索剂量反应关系和潜在的非线性关联.
主要方法:
- 分析了17988名参与国家健康和营养检查调查 (NHANES) (2007-2018) 的数据.
- 基于16种饮食和4种生活方式因素计算OBS.
- 使用多重逻辑回归和受限立方脊柱回归 (RCS) 来评估OBS和石患病率之间的关联.
主要成果:
- 较高的OBS与结石的患病率下降有显著的关联.
- 每增加一单位的OBS对应于结石发病率减少3% (OR=0.97).
- 与最低四分位数 (OR=0.65) 相比,OBS的最高四分位数显示结石的患病率明显较低.
- 在OBS和结石患病率之间观察到非线性负相关性.
结论:
- 较高的氧化平衡得分与一般成年人群中结石的患病率降低有关.
- 这些发现表明,促进导致较高OBS的因素可能对预防结石有益.
- 进一步的研究可以探索特定的饮食和生活方式干预措施,以改善OBS并减少结石风险.
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