基于PHQ-9得分的抑郁症和不孕症之间的关联:NHANES 2013-2018年的分析
1Department of Pharmacy, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
PloS one
|July 22, 2024
概括
抑郁症与生育年龄妇女的不孕症有关. 这种关联似乎非线性,效应在抑郁症得分为13时停滞不前.
科学领域:
- 生殖健康 生殖健康
- 心理健康 心理健康
- 流行病学 流行病学
背景情况:
- 关于抑郁症与不孕不育之间的联系,国家数据有限.
- 这项研究通过检查生育年龄妇女的这种关联来解决这一差距.
研究的目的:
- 为了研究抑郁症和不孕不育之间的关系.
- 探索这种关联中潜在的非线性模式和人口变化.
主要方法:
- 利用了来自NHANES (2013-2018) 的3,654名女性 (18-45岁) 的数据.
- 定义不孕症是试图怀孕1年没有成功.
- 使用患者健康问卷 (PHQ-9) 评估抑郁症,并采用逻辑回归和光滑曲线分析.
主要成果:
- 在较高的PHQ-9分数和不孕症之间发现了统计学意义上的关联 (OR1.04,P=0.010).
- 抑郁症与不孕不育的关系呈现出非线性模式,在PHQ-9得分为13时和.
- 这种关联在各个年龄组中是一致的,但根据种族/种族而异.
结论:
- 抑郁症与生育年龄妇女的不孕症有关.
- 研究结果表明,将心理健康纳入不孕症管理中.
- 限制包括横截面设计和潜在的回忆偏差.
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