一项新型试点研究,评估无线贴片系统在慢性恶心和吐患者中的有效性和安全性
Brian E Lacy1, David J Cangemi1, Joseph M Accurso2
1Division of Gastroenterology & Hepatology, Mayo Clinic, Jacksonville, Florida, USA.
Neurogastroenterology and motility
|July 22, 2024
概括
长时间的无线贴片监测在功能性消化不良 (FD) 和胃衰竭 (GP) 患者中显示出明显的胃肌电活动模式,有助于诊断和理解症状.
科学领域:
- 胃肠病学 胃肠病学
- 生理学 生理学 生理学
- 医疗器械 医疗器械
背景情况:
- 胃感觉运动障碍,包括功能性消化不良 (FD) 和胃 (GP),是常见的,并显著影响患者的生活质量.
- 使用无线运动补丁进行长时间的门诊记录,为收集这些患者的详细生理数据提供了一种新的方法.
研究的目的:
- 研究长期无线贴片监测在特征胃感觉运动障碍中的有用性.
- 确定与功能性消化不良和延迟胃空化的独特胃肠肌电活动模式.
主要方法:
- 被转诊用于胃空化扫描 (GES) 的成年患者被纳入.
- 三个无线运动补丁被应用到6天的门诊记录中,患者通过iPhone应用程序记录饮食,症状和肠道排便.
- 排除标准包括先前的前肠外科手术,使用某些药物,不受控制的糖尿病和最近住院治疗.
主要成果:
- 分析了23名患者 (87%为女性,平均年龄为43.9岁).
- 胃肌电活动较弱与4小时后胃空气延迟相关.
- 在患有恶心和吐的患者中观察到强烈的肠道活动.
- 功能性消化不良患者表现出胃和肠道肌电活性较弱,整个胃肠道的食反应减弱.
结论:
- 在患有功能性消化不良和延迟胃空化的患者中,确定了明显的胃肠肌电活动模式.
- 在一些功能性消化不良患者中,食后全肠肌电活性降低可能是症状的基础.
- 门诊无线监测可以揭示独特的病理生理模式和与饮食相关的活动,区分胃感觉运动疾病状态.
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