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时间分辨率的离子移动质谱揭示了模块化多基合成物分解过程中的结构转变

Chunyi Zhao1, Samuel T Slocum2, David H Sherman2

  • 1Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States.

Journal of the American Society for Mass Spectrometry
|July 22, 2024
PubMed
概括

离子移动性质谱检测揭示了1型聚基酸合成酶 (PKS) 合成酶-转移酶 (KS-AT) 双元体的不同构造状态和分解途径,从而促进了对药物天然产品的理解.

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