[胸腔淋巴腺病在COVID-19中的流行率和预后作用]
概括
胸腔淋巴腺症是COVID-19患者常见的发现,显著增加死亡风险. 这一元分析证实了它作为2019年冠状病毒病的重要预后指标的作用.
科学领域:
- 医疗成像医学成像
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- "COVID-19"疫情对全球健康构成重大威胁.
- 在COVID-19患者中胸腔淋巴腺病的预后价值仍然不确定.
研究的目的:
- 进行一项元分析,检查胸部淋巴腺病变在预测COVID-19患者30天死亡率中的预后作用.
主要方法:
- 在2021年6月之前,对MEDLINE,Cochrane和SCOPUS数据库进行了系统的文献搜索.
- 包括包括4621名患者的21项研究,研究质量使用纽卡斯尔-太华尺度进行评估.
- 用RevMan 5.3与随机效应模型进行了元分析.
主要成果:
- 在COVID-19患者中,胸腔淋巴腺病的综合患病率为16.7%.
- 胸腔淋巴腺病症患者 (34.7%) 的住院死亡率高于没有胸腔淋巴腺病症患者 (20.0%).
- 胸腔淋巴腺病与死亡率增加2.13倍相关 (p < 0.001).
结论:
- 胸腔淋巴腺病症在16.7%的COVID-19病例中存在.
- 胸腔淋巴腺病的存在与近两倍的医院死亡风险增加有关.
- 胸腔淋巴腺病变是COVID-19患者的显著预后因素.
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