在MRKH的骨盆和泛性持续疼痛综合征的经验:一个范围审查
R U Gaikaiwari1, C Prinsloo1, S R Grover2
1James Cook University, Cairns, Queensland, Australia.
Journal of pediatric and adolescent gynecology
|July 22, 2024
概括
梅耶 - 罗基坦斯基 - 库斯特 - 豪泽综合征 (MRKH) 与盆腔疼痛有关,特别是那些有子宫残留的患者的周期性疼痛. 对于理解MRKH患者没有残留和普遍性持续性疼痛综合征的疼痛,存在研究缺口.
科学领域:
- 生殖医学 生殖医学
- 疼痛综合征 疼痛综合征
- 医学遗传学 医学遗传学
背景情况:
- 梅耶-罗基坦斯基-库斯特-豪瑟综合征 (MRKH) 涉及子宫和阴道的先天性缺失,可能伴有其他异常.
- 在患有MRKH综合征的个体中,关于盆腔疼痛和相关疼痛综合征的研究有限.
研究的目的:
- 对MRKH的骨盆和一般性持续性疼痛综合征进行现有文献的范围审查.
- 为了确定MRKH疼痛管理的未来研究方向的知识差距.
主要方法:
- 根据乔安娜·布里格斯研究所框架进行范围审查.
- 在多个数据库 (MEDLINE,CINAHL,Scopus,Cochrane,Embase,Emcare) 搜索相关的文章.
- 数据分析涉及描述和分析方法,对选定的文章进行双重独立审查.
主要成果:
- 39篇文章描述了1353例MRKH病例,在选了3348篇文章后,符合纳入标准.
- 四项研究报告了基线骨盆疼痛,19项描述了急性表现,13项详细介绍了MRKH患者的干预后疼痛水平.
结论:
- 周期性盆腔疼痛在有子宫残留的MRKH患者中更常见; 没有残留的患者的疼痛是不太了解的.
- 没有研究在MRKH人群中解决了普遍性持续性疼痛综合征.
- 需要进一步进行横截面研究,以确定MRKH中疼痛综合征的患病率和严重程度.
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