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Updated: Jun 20, 2025

Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry
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Published on: July 26, 2019

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基,活性PKM2抑制IP3受体,可能需要GRP75作为额外的相互作用伙伴

Fernanda O Lemos1, Ian de Ridder1, Larry Wagner2

  • 1Laboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine & Leuven Kanker Instituut, KU Leuven, Herestraat 49, Campus Gasthuisberg O&N1 - B802, 3000 Leuven, Belgium.

Biochimica et biophysica acta. Molecular cell research
|July 22, 2024
PubMed
概括

酸激酶M2 (PKM2) 四聚体形成通过与伊诺西1,4,5-三酸盐受体 (IP3R) 相互作用来抑制信号. 这种相互作用是由GRP75调节的,形成了一个调节细胞水平的复合体.

关键词:
Bcl-2 的使用方法.卡2+) 信号传递方式这是一种D5SD.在 GRP75 中,GRP75 是IP(3) 接收器 接收器酸盐激酶M2的使用方法

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