社区暴力和喘:一项审查
Lisa Frueh1, Rachit Sharma1, Perry E Sheffield2
1Department of Environmental and Occupational Health, Drexel University Dornsife School of Public Health, Philadelphia, Pennsylvania.
接触暴力与喘发病率和严重程度的增加有关. 本综述总结了证据,并讨论了压力,行为和表观遗传机制,以及控制喘的临床影响.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 心理社会压力因素 心理社会压力因素
背景情况:
- 超过20年的流行病学研究表明,暴力暴露与喘之间存在一致的联系.
- 多种不同的人口和研究设计证实了社区暴力和喘之间的不良关联.
- 最近的研究强调了暴力作为心理社会压力因素对呼吸系统健康的影响.
研究的目的:
- 审查和综合有关暴力暴露和喘的流行病学证据.
- 专注于过去5年的研究和开创性研究.
- 讨论暴力和喘之间的潜在生物和行为机制.
主要方法:
- 发表的流行病学文献的系统审查.
- 对检查社区暴力暴露的研究进行分析.
- 关于暴力对喘的直接和间接影响的综合证据.
主要成果:
- 一致的证据表明,暴力暴露与喘发病率/恶化之间存在显著的关联.
- 研究强调了与压力相关的行为和表观遗传路径.
- 暴露于暴力可能会增加对环境触发因素 (如空气污染) 的易感性.
结论:
- 暴露于暴力是喘的重要环境风险因素.
- 了解机制对于开发有针对性的干预措施至关重要.
- 临床策略应在喘管理中解决心理社会压力因素.
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