Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Contingency Table01:29

Contingency Table

2.5K
A contingency table provides a way of portraying data that can facilitate calculating probabilities. It is a method of displaying a frequency distribution as a table with rows and columns to show how two variables may be dependent (contingent) upon each other; The table helps determine conditional probabilities quite quickly and can help systematically organize, analyze and quantify data. The table displays sample values concerning two variables that may be dependent or contingent on one...
2.5K
Multi-species Conserved Sequences02:51

Multi-species Conserved Sequences

3.9K
Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
3.9K
Kendall's Coefficient of Concordance01:20

Kendall's Coefficient of Concordance

307
Kendall's Coefficient of Concordance (W), also known as Kendall's W, is a non-parametric statistical measure used to assess the agreement or concordance between multiple raters or judges when they rank a set of items. It is often used when you have ordinal data (ranks) and you want to see if there is consistency or consensus among the raters. It is widely applied in research areas such as psychology, medicine, and social sciences, where multiple judges are asked to rank or rate subjects...
307
Accuracy, limits, and approximation01:28

Accuracy, limits, and approximation

445
Accuracy, limits, and approximations are common in many fields, especially in engineering calculations. These concepts are imperative for ensuring that a given value is as close as possible to its true value.
Accuracy is defined as the closeness of the measured value to the true or actual value. In engineering mechanics, repeated measurements are taken during theoretical or experimental analyses to ensure that the result is precise and accurate.
The accuracy of any solution is based on the...
445
Conserved Binding Sites01:49

Conserved Binding Sites

4.2K
Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally...
4.2K
Reliability and Validity01:29

Reliability and Validity

12.7K
Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
12.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Delivering effective non-invasive ventilation in amyotrophic lateral sclerosis using intensive remote support (DENIM): protocol for an embedded process evaluation in a hybrid type 3 implementation-effectiveness trial.

Implementation science communications·2026
Same author

A systematic review of the methodological quality of randomised trials in IBD surgery.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2026
Same author

Sigmoid volvulus part 1: Understanding patient experiences and priorities.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2026
Same author

Association between age and surgical resection for patients with stage II or III colorectal cancer: national study.

BJS open·2026
Same author

Medical therapy in mild autonomous cortisol secretion.

Journal of the Endocrine Society·2026
Same author

Burden of non-cancer comorbidities and mortality in chronic pancreatitis: a retrospective cohort study.

BMJ open gastroenterology·2026
Same journal

Harms Reporting Was Frequently Incomplete or Discordant in Biomedical Randomized Trials Published in 2023: A Meta-epidemiological Study.

Journal of clinical epidemiology·2026
Same journal

Using an Open Science Checklist in Grant Proposal Reviews to Predict Reproducibility of Funded Publications.

Journal of clinical epidemiology·2026
Same journal

A comparison of five statistical methods used to analyse longitudinal EORTC QLQ-C30 quality of life scores in randomised controlled trials: a simulation study.

Journal of clinical epidemiology·2026
Same journal

Sample Size Determination for Decision-centered Pragmatic Trials.

Journal of clinical epidemiology·2026
Same journal

Many multicenter randomized controlled trials do not account for center effect: a methodological review.

Journal of clinical epidemiology·2026
Same journal

Patient Acceptability of the Modified Zelen Approach to Randomized Trials - A Survey of the CAPS THA Cohort.

Journal of clinical epidemiology·2026
查看所有相关文章

相关实验视频

Updated: Jun 20, 2025

A Protocol for Computer-Based Protein Structure and Function Prediction
16:41

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

68.6K

评论:使用共识方法的核心描述符集支持"表一"一致性.

Matthew J Lee1, Segun Lamidi2, Kate M Williams3

  • 1Institute for Applied Health Research, University of Birmingham, Birmingham, UK.

Journal of clinical epidemiology
|July 22, 2024
PubMed
概括
此摘要是机器生成的。

在临床研究中标准化患者数据报告对于可重复性至关重要. 核心描述器集为跨研究的一致数据收集和分析提供了解决方案.

关键词:
达成共识 达成共识数据分析数据分析文件 文档 文档 文档 文档流行病学研究设计设计.作为主题的指导方针预测 预后 预测 预测出版 出版 出版 出版 出版结果的可复制性 结果的可复制性研究设计研究设计研究设计风险因素 风险因素

更多相关视频

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group
07:49

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group

Published on: August 16, 2017

7.0K
Cryo-EM and Single-Particle Analysis with Scipion
09:06

Cryo-EM and Single-Particle Analysis with Scipion

Published on: May 29, 2021

3.8K

相关实验视频

Last Updated: Jun 20, 2025

A Protocol for Computer-Based Protein Structure and Function Prediction
16:41

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

68.6K
Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group
07:49

Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group

Published on: August 16, 2017

7.0K
Cryo-EM and Single-Particle Analysis with Scipion
09:06

Cryo-EM and Single-Particle Analysis with Scipion

Published on: May 29, 2021

3.8K

科学领域:

  • 临床研究方法论 临床研究方法论
  • 数据标准化数据标准化
  • 科学中的可复制性

背景情况:

  • 在临床研究中,对患者特征的不一致报告妨碍了可复制性,限制了分析.
  • 建议使用特定条件的"核心描述器集"进行标准化表1报告.
  • 关键因素包括人口统计,疾病严重程度,并发症和预后.

研究的目的:

  • 提出和开发特定条件的核心描述器集,以便在临床研究中标准化患者特征报告.
  • 提高临床研究的可复制性和分析潜力.
  • 促进医学研究中的数据共享和知识建设.

主要方法:

  • 利益相关者参与描述符识别和价值评级.
  • 使用多个Delphi轮进行系统的识别和达成共识.
  • 通过专家会议达成最终协议.

主要成果:

  • 为临床研究开发标准化的核心描述器集.
  • 建立基于共识的方法来定义患者的基本特征.
  • 表1中的患者数据的一致报告框架.

结论:

  • 核心描述器集可以更轻松地进行交叉研究比较和个人患者的元分析.
  • 促进常规数据分析,子组识别和风险分层.
  • 提高临床特征,个性化,可重复性,数据共享和知识构建,同时最大限度地降低研究负担.