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Updated: Jun 20, 2025

Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells
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检查点抑制剂诱导的自身免疫糖尿病:一种自身炎症性疾病

Zoe Quandt1, Ana Perdigoto2,3, Mark S Anderson1

  • 1Department of Internal Medicine and Diabetes Center, University of California San Francisco, San Francisco, California 94115, USA.

Cold Spring Harbor perspectives in medicine
|July 22, 2024
PubMed
概括

针对免疫检查点的癌症免疫疗法可以导致自身免疫性糖尿病. 以前存在的遗传风险和自身抗体,以及升高的脂酶,可以预测这种副作用,特别是PD-1/PD-L1阻塞.

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