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针对细胞外线粒体阿斯巴提尔-tRNA合成酶的向降解调节免疫反应

Benjamin S Johnson1, Daniela Farkas1, Rabab El-Mergawy1

  • 1Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, The Ohio State University, Columbus, OH, USA.

Nature communications
|July 22, 2024
PubMed
概括

阿斯巴提尔-tRNA合成酶 (DARS2),一种线粒体蛋白质,在细菌性肺炎期间增强先天免疫力和细胞修复. 它的水平由FBXO24调节,为免疫增强疗法提供了一个目标.

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