研究平均最大的模值值作为前列腺癌的新诊断参数
Jieyu Duan1, ZhanHui Liu2, Zhong Li3
1Department of Ultrasound, First Affiliated Hospital of Zhengzhou University, Zhengzhoug City, 450052, Henan Province, China.
Scientific reports
|July 22, 2024
概括
跨直肠切割波弹性图 (TSWEUI) 提供了一种通过测量组织硬度来诊断前列腺癌 (PCa) 的新方法. 这种技术,使用平均最大的Young.
科学领域:
- 医疗成像医学成像
- 在瘤学瘤学.
- 生物物理学的生物物理.
背景情况:
- 前列腺癌 (PCa) 诊断通常依赖于侵入性方法.
- 剪波弹性图 (SWE) 是一种非侵入性的超声波技术,用于评估组织硬度.
- 缺少跨直肠SWE超声成像 (TSWEUI) 和模量计算的标准化方法.
研究的目的:
- 为了评估一个新参数的有效性,从TSWEUI获得的平均最大Young模量 (m-Emax),用于PCa诊断.
- 开发和验证PCa概率的预测模型,其中包括m-Emax.
- 将m-Emax的诊断性能与磁共振成像 (MRI) 进行比较,并评估TSWEUI的成本效益.
主要方法:
- 一项对209名疑似PCa.患者的回顾性研究.
- 75名患者进行了TSWEUI,m-Emax从四个象限中的12次测量中计算出来.
- 使用前列腺体积,前列腺特异性抗原 (PSA) 和m-Emax开发了一个名图,以预测PCa概率.
主要成果:
- 在75名患者中,m-Emax的接收器运行特征曲线 (AUC) 下的面积为0.754.
- 纳入m-Emax的nomogram获得了0.868的AUC,证明了有效的PCa概率预测.
- 在63名患者 (P=0.361) 中,m-Emax (AUC=0.717) 和MRI (AUC=0.787) 之间没有发现统计学上显著的差异.
结论:
- 平均最大Young模量 (m-Emax) 是使用TSWEUI进行PCa诊断的一个有希望的参数.
- 整合m-Emax的nomogram可以帮助PCa诊断,并可能减少不必要的活检.
- TSWEUI为诊断前列腺癌提供了MRI的经济有效的替代方案.
更多相关视频
10:55Extracting the Young's Modulus of Native Murine Pulmonary Basement Membranes from Atomic Force Microscopy Derived Force Maps
Published on: January 31, 2025
328
06:16A Probing Device for Quantitatively Measuring the Mechanical Properties of Soft Tissues during Arthroscopy
Published on: May 1, 2020
5.5K
相关概念视频
Dynamic Modulus of Elasticity of Concrete
297
The dynamic modulus of elasticity assesses how a concrete structure deforms under impact or dynamic loads. It is typically higher than the static modulus of elasticity, measured under slow, steady loading conditions.
The sonic test is a common method to determine the dynamic modulus. In this test, a concrete beam, sized either 6 x 6 x 30 inches or 4 x 4 x 20 inches, is clamped at its center. Vibrations are initiated at one end of the beam by an electromagnetic exciter unit powered by...
The sonic test is a common method to determine the dynamic modulus. In this test, a concrete beam, sized either 6 x 6 x 30 inches or 4 x 4 x 20 inches, is clamped at its center. Vibrations are initiated at one end of the beam by an electromagnetic exciter unit powered by...
297
Strain and Elastic Modulus
3.6K
The quantity that describes the deformation of a body under stress is known as strain. Strain is given as a fractional change in either length, volume, or geometry under tensile, volume (also known as bulk), or shear stress, respectively, and is a dimensionless quantity. The strain experienced by a body under tensile or compressive stress is called tensile or compressive strain, respectively. In contrast, the strain experienced under bulk stress and shear stress is known as volume and shear...
3.6K
Elasticity in Concrete
88
Upon subjecting concrete to moderate or high uniaxial compressive or tensile stresses, the strain response is non-linear relative to the stress applied. As the stress is removed, the resulting stress-strain curve deviates from the original path traced during loading, creating a hysteresis loop, indicative of the concrete's non-linear and non-elastic properties. Typically, a material's modulus of elasticity, which is a measure of the material's stiffness, is inferred from the linear...
88
Hooke's Law
369
Hooke's law, a pivotal principle in material science, establishes that the strain a material undergoes is directly proportional to the applied stress, defined by a factor called the modulus of elasticity or Young's modulus.
369
Disorders of the Male Reproductive System
377
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
377
Bulk Modulus
299
The bulk modulus is a scientific term used to describe a material's resistance to uniform compression. It is the proportionality constant that links a change in pressure to the resulting relative volume change.
299
