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Updated: Jun 20, 2025

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
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Published on: December 29, 2021

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通过点击编辑,可以使用DNA聚合酶和HUH内核酶进行可编程的基因组编写

Joana Ferreira da Silva1,2,3, Connor J Tou1,2,4, Emily M King1,2,5

  • 1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.

Nature biotechnology
|July 22, 2024
PubMed
概括

点击编辑是一种新的基因组编写平台,使用DNA依赖的聚合酶和RNA可编程的尼克酶来安装精确的DNA编辑. 这种多功能技术在人类细胞中实现了高效的多样化基因组修改.

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