中枢神经系统的原发性扩散性大B细胞淋巴瘤被认定为CSF生物标志物
Valentin Loser1, Amandine Segot2, Laurence de Leval3
1Department of Clinical Neurosciences, Service of Neurology, Lausanne University Hospital (CHUV)and, University of Lausanne , CHUV-BH07, Lausanne, Switzerland. valentin.loser@chuv.ch.
BMC neurology
|July 22, 2024
概括
诊断原发性中枢神经系统淋巴瘤 (PCNSL) 是很困难的. 新的脑脊液 (CSF) 生物标志物,包括MYD88突变和特定蛋白质水平,显示出更早检测PCNSL的前途.
科学领域:
- 神经学 神经学
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
背景情况:
- 中枢神经系统 (PCNSL) 的原发性扩散性大B细胞淋巴瘤存在诊断挑战,常规方法如MRI,CSF细胞学和流细胞计通常产生低灵敏度.
- 大脑活检虽然确切,但可能会误导,导致诊断延迟和治疗启动.
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