甲状腺相关眼科医症中的光学连贯性断层扫描血管学:系统性审查
Mohammad Taher Rajabi1, Reza Sadeghi1,2, Mohammad Reza Abdol Homayuni1,2
1Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Zip Code: 1336616351, Tehran, Iran.
BMC ophthalmology
|July 22, 2024
概括
光学一致性断层扫描血管图 (OCTA) 揭示了甲状腺相关眼科病 (TAO) 的血流变化. OCTA有助于早期检测TAO,并监测治疗的有效性.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 内分泌学 在内分泌学.
背景情况:
- 甲状腺相关的眼科医症 (TAO) 影响眼部组织,包括胆管和视神经头部 (ONH).
- 评估TAO的微血管变化对于了解疾病进展和指导治疗至关重要.
研究的目的:
- 在TAO患者中使用光学一致性断层扫描血管学 (OCTA) 参数系统地审查和评估胆道,黄斑和周围细胞血流的变化.
- 评估特定视网膜层和视神经头部内血管和 perfusion 密度的变化.
主要方法:
- 对多个科学数据库 (PubMed,Scopus等) 的系统审查. 进行了.执行了.
- 包括的研究重点是TAO患者的OCTA参数变化,评估血管密度,输液和状血管区 (FAZ) 范围.
- 对已发表的研究进行了质量评估.
主要成果:
- 分析了42项研究,检查了OCTA参数,如毛细胞流量,视网膜微血管密度 (表面和深层视网膜),斑点血管密度和ONH/RPC血管密度.
- 评估了OCTA发现与临床参数 (如视敏度和视野缺陷) 之间的相关性.
- 考虑了体,周体和副体密度的数据,以及黄斑整体图像血管密度 (m-wiVD) 和ONH/RPC整体图像血管密度 (onh-wiVD,rpc-wiVD).
结论:
- OCTA对于区分活性与非活性TAO以及识别患有或没有双甲状腺视神经病变 (DON) 的患者是有价值的.
- OCTA的措施显示出高灵敏度和特异性的TAO早期检测的前景,有可能防止不可逆转的视力丧失.
- OCTA可以评估TAO治疗的有效性,如皮质类固醇治疗和手术减压.
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