开发和验证一个名图,以进行术前预测直肠癌外科手术后的永久性静脉栓塞:一个回顾性队列研究
Chenglin Tang1, Fan He1, Fuyu Yang1
1Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
BMC cancer
|July 22, 2024
概括
临时静脉切除术 (TI) 有助于预防严重的直肠癌手术并发症. 这项研究确定了永久性静脉管 (PS) 形成的术前预测因素,并开发了一个名谱来帮助手术决策并改善患者的治疗结果.
科学领域:
- 结肠直肠手术 结肠直肠手术
- 手术瘤学手术瘤学
- 患者的治疗结果.
背景情况:
- 临时静脉切除术 (TI) 用于减少直肠癌手术后的严重并发症,如静脉切除泄漏.
- 然而,一些患者患上永久性静脉口腔 (PS),影响生活质量.
- 预测PS对于优化手术策略至关重要.
研究的目的:
- 为了确定直肠癌切除后永久性静脉管 (PS) 的术前预测因素.
- 开发和验证PS的预测模型,以改善患者的生活质量.
主要方法:
- 对403名接受TI的直肠癌患者进行了回顾性分析.
- 后勤回归分析以确定PS的独立风险因素.
- 开发和验证使用ROC分析进行手术前的诺姆图.
主要成果:
- 58名患者 (14.39%) 患有永久性静脉口腔 (PS).
- 关键的手术前预测因素包括瘤位置,瘤标志物,ASA得分,T4阶段,淋巴结转移和远程转移.
- 建立了一个经过验证的名图,AUC为0.7758.8.
结论:
- 确定了六个独立的PS手术前风险因素.
- 经过验证的诺米图可以帮助外科医生为高风险患者选择最佳的外科选择.
- 该工具旨在改善手术决策和患者的生活质量.
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