患有非小细胞肺癌的患者肺部感染的危险因素:元分析
1Department of Oncology, Quanzhou hospital of traditional Chinese medicine, No.388, Sunjiang Road, Jinlong Subdistrict, Licheng District, Quanzhou City, Fujian Province, China. zlkcj2024@126.com.
糖尿病,放射治疗和长期手术增加非小细胞肺癌 (NSCLC) 患者的肺部感染风险. 这些因素的早期识别有助于实施预防策略,以减少感染发生率.
科学领域:
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
- 临床研究 临床研究
背景情况:
- 肺部感染对非小细胞肺癌 (NSCLC) 患者构成重大威胁.
- 识别风险因素对于制定有效的预防策略至关重要.
研究的目的:
- 评估和检查与NSCLC患者肺部感染相关的风险变量.
- 为此群体肺部感染的临床预防提供基于证据的建议.
主要方法:
- 在多个数据库 (CNKI,Wanfang,VIP,CBM,PubMed,Web of Science,Cochrane Library) 进行了系统的文献搜索,截至2023年12月.
- 包括的研究是随机对照试验,重点关注肺部感染的NSCLC.
- 研究质量使用NOS尺度进行评估,异质性使用Q测试进行评估.
主要成果:
- 这项分析包括了10项涉及957名参与者的研究.
- 在NSCLC患者中发现肺部感染的关键风险因素包括糖尿病,低albuminemia,放射治疗和手术持续时间超过180分钟.
- 年龄,性别,吸烟状况,腺癌亚型,晚期TNM阶段 (III-IV) 和高血压等因素与增加的肺部感染风险没有显著相关.
结论:
- 糖尿病,放射治疗和超过180分钟的手术是NSCLC患者肺部感染的重要风险因素.
- 快速识别这些风险因素对于实施有针对性的预防措施至关重要.
- 积极的临床管理可以有效地减少NSCLC患者肺部感染的发生率.
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