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Updated: Jun 20, 2025

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
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Published on: September 30, 2016

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结直肠癌的临床病理学,分子和预后特征具有KRAS c.34G>T (p.G12C) 突变

Satoko Ugai1,2, Qian Yao1, Yasutoshi Takashima1,3

  • 1Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts, USA.

Cancer science
|July 23, 2024
PubMed
概括

KRAS p.G12C突变定义了一个独特的结直肠癌亚型,具有独特的分子和临床特征. 这些瘤表现出改变的甲基化模式,并与增加的死亡率有关,这表明向治疗可能是有益的.

关键词:
克拉斯 (Kras) 是一个国家.CpG岛屿甲基化剂表型它们是有侵略性的.结直肠瘤是什么意思这就是Sotorasib.

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Simple and Rapid Method to Obtain High-quality Tumor DNA from Clinical-pathological Specimens Using Touch Imprint Cytology11:20

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