评估促进公平的干预措施,以防止在流感结果中基于种族的不平等
Erin Stafford1,2, Dobromir Dimitrov1,3, Susan Brown Trinidad4
1Department of Applied Mathematics, University of Washington, Seattle, WA, USA.
medRxiv : the preprint server for health sciences
|July 23, 2024
概括
减少工作接触和均等接种疫苗率可以减少所有群体的症状性流感感染和住院治疗. 针对伴随性疾病的干预措施显著减少了住院治疗,特别是在BIPOC社区,改善了每个人的结果.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 计算机建模 计算建模
背景情况:
- 季节性流感在美国导致大量住院治疗.
- 黑人,土著和其他有色人种 (BIPOC) 社区面临不成比例的高负担.
研究的目的:
- 量化各种缓解策略对流感结果不平等的影响.
- 评估促进公平的干预措施在减少差距方面的有效性.
主要方法:
- 开发了一种以种族分层的流感传播的基于代理的流感传播模型.
- 该模型与五个种族族群的美国人口和住院数据相匹配.
- 模拟了五种理想化的干预措施:均等的疫苗接种,均等的并发病,比例的工作风险,减少工作接触和组合.
主要成果:
- 减少工作接触或使疫苗接种率相等,在BIPOC成年人中,症状性感染减少了高达17%.
- 减少并发病症使BIPOC组的住院病例减少了40%以上.
- 所有干预措施都减少了所有种族和种族群体流感住院不平等.
结论:
- 均等接种疫苗和减少工作接触是减少流感不平等和整体感染/住院的有效策略.
- 针对并发症的干预措施显示,住院病例减少最为显著,使所有群体受益.
- 简单的,可实施的策略可以大大减轻流感差异.
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