芬兰的囊性纤维化患者特征和医疗保健资源利用情况,使用链接的注册表
Kirsi Malmivaara1, Mari Pölkki2, Tuire Prami2
1Helsinki University Hospital, Helsinki, Finland.
Heliyon
|July 23, 2024
概括
芬兰的囊性纤维化 (CF) 患病率较低,诊断往往延迟. 与对照组相比,芬兰CF患者经常使用抗生素,住院率明显高.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 现实世界的证据.
背景情况:
- 芬兰的囊性纤维化 (CF) 患病率和医疗保健利用率没有得到充分的记录.
- 了解这些因素对于有效的公共卫生战略和资源分配至关重要.
研究的目的:
- 确定芬兰CF的流行率和流行病学.
- 分析芬兰CF患者的医疗保健资源利用情况,包括并发症和药物使用情况.
- 将CF患者与匹配的对照组之间的医疗保健使用情况进行比较.
主要方法:
- 一个基于人口的匹配队列研究,利用芬兰国家注册表的链接.
- 对102名CF患者 (2015-2019) 的电子医疗数据和药物购买情况进行分析.
- 根据性别,年龄和居住地匹配5倍的对照人群;评估并发病,药物和年度医院服务使用情况.
主要成果:
- 芬兰CF患病率为每10万人口1.85,诊断时的中位年龄为1岁.
- 常见的并发病包括慢性鼻炎 (39.2%) 和肺炎 (38.2%).
- 抗生素 (99.0%) 和胰腺酶 (84.3%) 是购买最多的药物;在CF队列中,住院医院访问量是CF队列的30倍以上.
结论:
- 芬兰CF患病率低可能与独特的人口特征和延迟诊断有关.
- 经常使用抗生素是芬兰CF护理的特点.
- 显著增加的住院医院利用率凸显了CF对医疗保健资源的巨大负担.
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