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在患有脊柱长期动脉静脉囊患者中,术后晚期恶化的危险因素
Yuanhong Ge1, Qingjia Lai2, Wei Guo3
1Department of Neurosurgery, Chengdu Second People's Hospital, Chengdu, China.
Frontiers in neurology
|July 23, 2024
概括
用内血管治疗 (EVT) 治疗的脊柱持续性动脉静脉患者或患有严重手术前神经功能障碍的人面临着手术后晚期恶化的更高风险. 与EVT相比,微手术可能会降低晚期恶化的风险.
科学领域:
- 神经外科 神经外科
- 血管外科 血管外科
- 神经学 神经学
背景情况:
- 脊柱持续性动脉静脉 (SDVAF) 通常在手术后得到改善,但晚期恶化 (LD) 影响12%-55.8%的患者.
- 在SDVAF患者晚期恶化的危险因素仍然不清楚.
- 这项研究旨在确定SDVAF患者晚期恶化的预测因素.
研究的目的:
- 探索脊柱持续动脉静脉囊 (SDVAFs) 患者晚期恶化的风险因素 (LD).
- 确定SDVAFs治疗后晚期恶化的独立预测因素.
主要方法:
- 从2014年6月至2022年5月期间接受治疗的105名SDVAF患者的临床数据的回顾性审查.
- 使用修改的阿米诺夫和洛格尺度评估神经功能障碍的严重程度.
- 单变量和多变量考克斯回归分析以确定LD的风险因素.
主要成果:
- 多变量分析显示,微手术 (MS) 与内血管治疗 (EVT) 相比,与LD风险较低有关.
- 严重的手术前神经功能障碍 (NDF) 是LD的重要危险因素 (HR 3.604).
- 与轻度NDF相比,中度NDF的LD风险与轻度NDF (HR 1.352) 相似.
结论:
- 内血管治疗 (EVT) 是SDVAF患者晚期恶化的独立风险因素.
- 严重的手术前神经功能障碍是晚期恶化的独立风险因素.
- 与EVT相比,微手术可能与晚期恶化的风险较低.
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