生物技术的新发展适用于微生物
EFSA journal. European Food Safety Authority
|July 23, 2024
概括
对微生物应用的新基因组技术 (NGT) 与既有方法相比没有新的危险. 欧洲粮食安全局 (EFSA) 在
科学领域:
- 食品安全和生物技术
- 微生物学和基因工程学
- 食品和料中的风险评估
背景情况:
- 欧洲食品安全局评估了用于食品,料和环境释放的微生物的新基因组技术 (NGT).
- 视野扫描确定了NGT修饰的微生物 (NGT-Ms),预计在10年内出现在欧盟市场.
- 评估涵盖了可活的微生物 (4类) 和不可活的产品 (3类).
研究的目的:
- 提供关于NGT应用于食品,料和环境用途的微生物的科学意见.
- 与已建立的基因组技术 (EGT) 和常规突变发生学相比,评估与NGT-Ms相关的潜在新型危险.
- 评估现有的EFSA指南对NGT-Ms的适用性.
主要方法:
- 地平线扫描以识别NGT-Ms.
- 对NGT-Ms与EGT和常规突变发生的比较危险评估.
- 审查现有的EFSA指导文件.
主要成果:
- 与EGT或常规突变发生相比,NGT-Ms没有发现新的潜在危险.
- NGT的效率,特异性和可预测性可能会导致基因组改变相关的危险减少.
- 现有的EFSA指南部分适用,其中一些需要对NGT-Ms进行更新.
结论:
- 需要更新EFSA指南,因为有些指南对NGT-Ms.不够.
- 风险评估应在通过常规突变发生,EGT或NGT修饰的微生物中保持一致.
- 一个个案例的方法可能允许减少对特定NGT-Ms的要求.
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